TEMPLATE Oocyte and Embryo assessment (Oocyte and Embryo assessment)

TEMPLATE ID	Oocyte and Embryo assessment
Concept	Oocyte and Embryo assessment
Description	Not Specified
Purpose	Not Specified
References
Other Details (Language Independent)	MetaDataSet:Sample Set : Template metadata sample set
Language used	en
Citeable Identifier	1013.26.419
Root archetype id	openEHR-EHR-OBSERVATION.embryo_assessment.v0
Oocyte and embryo assessment	Oocyte and embryo assessment: Timed assessment of morphological features and development of a single oocyte or embryo during assisted reproduction treatment.
Data
Any event	Any event: Default, unspecified point in time or interval event which may be explicitly defined in a template or at run-time.
Data
Label	Label: Label or name identifying an oocyte or embryo.
ID	ID: The unique identifier for the oocyte or embryo. For example: the "Single European Code” or “SEC” identifier.
Description	Description: General description of the oocyte or embryo.
Developmental stage	Developmental stage: Developmental stage of the oocyte or embryo. Coded Text Oocyte Pronuclear stage 2-cell stage 4-cell stage 8-cell stage Morula Blastocyst Text
Developmental event	Developmental event: Recording of a developmental event observed during time-lapse microscopy. May record timed events, like extrusion of second polar body, appearance and fading of pronuclei, cell divisions, or compaction. Text Coded Text tPB2 extrusion tPNa tPNf t2 t3 t4 t5 t6 t7 t8 tSC tM tSB tB tE tHN tHB
Examination of an oocyte	Examination of an oocyte: Morphological findings obtained by microscopy of the human oocyte during assisted reproduction treatment.
Maturity of cumulus-oocyte complex	Maturity of cumulus-oocyte complex: Maturity of the entire intact cumulus-oocyte complex. Coded Text Mature Immature Postmature Very immature Text
Oocyte maturation stage	Oocyte maturation stage: Nuclear maturity of oocyte after removal of the cumulus-corona cell mass. Coded Text Metaphase 2 Meiosis 1 Germinal vesicle Text
Oocyte size	Oocyte size: Apparent size of the oocyte. Coded Text Normal Small Giant Text
Oocyte shape	Oocyte shape: Shape of the oocyte. Coded Text Round Ovoid or elongated. Text
Cytoplasmic morphology	Cytoplasmic morphology: Morphology of the oocyte cytoplasm. Coded Text Homogeneous Granular Vacuolated Plaques of dilated SER discs Refractile body Darkness Inclusions Text
Zona pellucida thickness	Zona pellucida thickness: Thickness of the zona pellucida. Coded Text Normal Thin Thich Text
Perivitelline space morphology	Perivitelline space morphology: Morphology of the perivitelline space. Coded Text Normal Large Small Debris Text
First polar body morphology	First polar body morphology: Morphology of the first polar body. Text Coded Text Normal smooth Ovoid rough Fragmented Large Degenerated
Metaphase spindle	Metaphase spindle: Morphology and position of the metaphase spindle obtained by polarized light microscopy. Text Coded Text Normal size Small Large Normal location Abnormal location
Other morphological features	Other morphological features: Additional morphological features not captured by specific parameters.
Time post-insemination	Time post-insemination: The duration since insemination.
Interpretation	Interpretation: Clinical interpretation of the morphological and developmental assessment of the oocyte or embryo. Coded Text Suitable for clinical use Unsuitable for clinical use Text
Comment	Comment: Additional narrative about the oocyte or embryo assessment, not captured in other fields. For example: difficulties in visualisation.
Fertilisation check	Fertilisation check: Observation of the inseminated oocyte to assess fertilization.
Data
Label	Label: Label or name identifying an oocyte or embryo.
ID	ID: The unique identifier for the oocyte or embryo. For example: the "Single European Code” or “SEC” identifier.
Description	Description: General description of the oocyte or embryo.
Developmental stage	Developmental stage: Developmental stage of the oocyte or embryo. Coded Text Oocyte Pronuclear stage 2-cell stage 4-cell stage 8-cell stage Morula Blastocyst Text
Developmental event	Developmental event: Recording of a developmental event observed during time-lapse microscopy. May record timed events, like extrusion of second polar body, appearance and fading of pronuclei, cell divisions, or compaction. Text Coded Text tPB2 extrusion tPNa tPNf t2 t3 t4 t5 t6 t7 t8 tSC tM tSB tB tE tHN tHB
Examination of a zygote	Examination of a zygote: Morphological findings obtained by microscopy of the human zygote during assisted reproduction treatment.
Number of pronuclei	Number of pronuclei: Number of visible pronuclei in a zygote.
Pronuclear symmetry	Pronuclear symmetry: Size symmetry of pronuclei in a zygote. Text Coded Text Symmetrical Non-symmetrical
Pronuclear morphology	Pronuclear morphology: Morphology of pronuclei in a zygote. Text Coded Text Centrally juxtaposed Separated Peripherally positioned
Polar body morphology	Polar body morphology: Morphology of polar bodies in a zygote. Text Coded Text Normal Separated Fragmented Degenerated
Cytoplasmic morphology	Cytoplasmic morphology: Morphology of the cytoplasm in a zygote. Text Coded Text Homogeneous Granular Vacuolated Dysmorphic
Nucleolar precursor bodies	Nucleolar precursor bodies: Distribution of nuclear precursor bodies in a zygote. Coded Text Normal Absent Bull's eye Text
Other morphological features	Other morphological features: Additional morphological features not captured by specific parameters.
Time post-insemination	Time post-insemination: The duration since insemination.
Interpretation	Interpretation: Clinical interpretation of the morphological and developmental assessment of the oocyte or embryo. Coded Text Suitable for clinical use Unsuitable for clinical use Text
Comment	Comment: Additional narrative about the oocyte or embryo assessment, not captured in other fields. For example: difficulties in visualisation.
Syngamy check	Syngamy check: Observation of the inseminated oocyte to assess syngamy.
Data
Label	Label: Label or name identifying an oocyte or embryo.
ID	ID: The unique identifier for the oocyte or embryo. For example: the "Single European Code” or “SEC” identifier.
Description	Description: General description of the oocyte or embryo.
Developmental stage	Developmental stage: Developmental stage of the oocyte or embryo. Coded Text Oocyte Pronuclear stage 2-cell stage 4-cell stage 8-cell stage Morula Blastocyst Text
Developmental event	Developmental event: Recording of a developmental event observed during time-lapse microscopy. May record timed events, like extrusion of second polar body, appearance and fading of pronuclei, cell divisions, or compaction. Text Coded Text tPB2 extrusion tPNa tPNf t2 t3 t4 t5 t6 t7 t8 tSC tM tSB tB tE tHN tHB
Examination of a zygote	Examination of a zygote: Morphological findings obtained by microscopy of the human zygote during assisted reproduction treatment.
Number of pronuclei	Number of pronuclei: Number of visible pronuclei in a zygote.
Pronuclear symmetry	Pronuclear symmetry: Size symmetry of pronuclei in a zygote. Text Coded Text Symmetrical Non-symmetrical
Pronuclear morphology	Pronuclear morphology: Morphology of pronuclei in a zygote. Text Coded Text Centrally juxtaposed Separated Peripherally positioned
Polar body morphology	Polar body morphology: Morphology of polar bodies in a zygote. Text Coded Text Normal Separated Fragmented Degenerated
Cytoplasmic morphology	Cytoplasmic morphology: Morphology of the cytoplasm in a zygote. Text Coded Text Homogeneous Granular Vacuolated Dysmorphic
Nucleolar precursor bodies	Nucleolar precursor bodies: Distribution of nuclear precursor bodies in a zygote. Coded Text Normal Absent Bull's eye Text
Other morphological features	Other morphological features: Additional morphological features not captured by specific parameters.
Time post-insemination	Time post-insemination: The duration since insemination.
Interpretation	Interpretation: Clinical interpretation of the morphological and developmental assessment of the oocyte or embryo. Coded Text Suitable for clinical use Unsuitable for clinical use Text
Comment	Comment: Additional narrative about the oocyte or embryo assessment, not captured in other fields. For example: difficulties in visualisation.
Early cleavage check	Early cleavage check: Observation of the embryo to assess early first cell cleavage.
Data
Label	Label: Label or name identifying an oocyte or embryo.
ID	ID: The unique identifier for the oocyte or embryo. For example: the "Single European Code” or “SEC” identifier.
Description	Description: General description of the oocyte or embryo.
Developmental stage	Developmental stage: Developmental stage of the oocyte or embryo. Coded Text Oocyte Pronuclear stage 2-cell stage 4-cell stage 8-cell stage Morula Blastocyst Text
Developmental event	Developmental event: Recording of a developmental event observed during time-lapse microscopy. May record timed events, like extrusion of second polar body, appearance and fading of pronuclei, cell divisions, or compaction. Text Coded Text tPB2 extrusion tPNa tPNf t2 t3 t4 t5 t6 t7 t8 tSC tM tSB tB tE tHN tHB
Examination of a cleavage-stage embryo	Examination of a cleavage-stage embryo: Morphological findings obtained by microscopy of the human cleavage-stage embryo during assisted reproduction treatment.
Number of cells	Number of cells: Number of cells in a cleavage-stage embryo.
Fragmentation	Fragmentation: Cytoplasmic fragmentation in a cleavage stage embryo. Coded Text None Mild fragmentation Moderate fragmentation Severe fragmentation Text Proportion
Blastomere size	Blastomere size: Relative blastomere size. Coded Text Equal Unequal Stage specific Non-stage specific Text
Nucleation	Nucleation: Presence or absence of nuclei in the blastomeres of the cleavage stage embryo. Coded Text No visible nuclei Mononucleation Binucleation Multinucleation Broad multinucleation Text
Cytoplasmic morphology	Cytoplasmic morphology: Morphology of the cytoplasm of cells in cleavage stage embryo. May contain description of abnomalies, such as granularity, pitting, and presence of vacuoles.
Spatial distribution of cells	Spatial distribution of cells: Spatial distribution of cells in a cleavage stage embryo. The cells of early embryo may be arranged in pyramidal, clover or irregular manner.
Compaction	Compaction: Degree of compaction in a cleavage stage embryo. Coded Text None Minimal Moderate Complete Text
Other morphological features	Other morphological features: Additional morphological features not captured by specific parameters.
Time post-insemination	Time post-insemination: The duration since insemination.
Interpretation	Interpretation: Clinical interpretation of the morphological and developmental assessment of the oocyte or embryo. Coded Text Suitable for clinical use Unsuitable for clinical use Text
Comment	Comment: Additional narrative about the oocyte or embryo assessment, not captured in other fields. For example: difficulties in visualisation.
Day-2 embryo assessment	Day-2 embryo assessment: Embryo observation on Day 2 post insemination.
Data
Label	Label: Label or name identifying an oocyte or embryo.
ID	ID: The unique identifier for the oocyte or embryo. For example: the "Single European Code” or “SEC” identifier.
Description	Description: General description of the oocyte or embryo.
Developmental stage	Developmental stage: Developmental stage of the oocyte or embryo. Coded Text Oocyte Pronuclear stage 2-cell stage 4-cell stage 8-cell stage Morula Blastocyst Text
Developmental event	Developmental event: Recording of a developmental event observed during time-lapse microscopy. May record timed events, like extrusion of second polar body, appearance and fading of pronuclei, cell divisions, or compaction. Text Coded Text tPB2 extrusion tPNa tPNf t2 t3 t4 t5 t6 t7 t8 tSC tM tSB tB tE tHN tHB
Examination of a cleavage-stage embryo	Examination of a cleavage-stage embryo: Morphological findings obtained by microscopy of the human cleavage-stage embryo during assisted reproduction treatment.
Number of cells	Number of cells: Number of cells in a cleavage-stage embryo.
Fragmentation	Fragmentation: Cytoplasmic fragmentation in a cleavage stage embryo. Coded Text None Mild fragmentation Moderate fragmentation Severe fragmentation Text Proportion
Blastomere size	Blastomere size: Relative blastomere size. Coded Text Equal Unequal Stage specific Non-stage specific Text
Nucleation	Nucleation: Presence or absence of nuclei in the blastomeres of the cleavage stage embryo. Coded Text No visible nuclei Mononucleation Binucleation Multinucleation Broad multinucleation Text
Cytoplasmic morphology	Cytoplasmic morphology: Morphology of the cytoplasm of cells in cleavage stage embryo. May contain description of abnomalies, such as granularity, pitting, and presence of vacuoles.
Spatial distribution of cells	Spatial distribution of cells: Spatial distribution of cells in a cleavage stage embryo. The cells of early embryo may be arranged in pyramidal, clover or irregular manner.
Compaction	Compaction: Degree of compaction in a cleavage stage embryo. Coded Text None Minimal Moderate Complete Text
Other morphological features	Other morphological features: Additional morphological features not captured by specific parameters.
Time post-insemination	Time post-insemination: The duration since insemination.
Interpretation	Interpretation: Clinical interpretation of the morphological and developmental assessment of the oocyte or embryo. Coded Text Suitable for clinical use Unsuitable for clinical use Text
Comment	Comment: Additional narrative about the oocyte or embryo assessment, not captured in other fields. For example: difficulties in visualisation.
Day-3 embryo assessment	Day-3 embryo assessment: Embryo observation on Day 3 post insemination.
Data
Label	Label: Label or name identifying an oocyte or embryo.
ID	ID: The unique identifier for the oocyte or embryo. For example: the "Single European Code” or “SEC” identifier.
Description	Description: General description of the oocyte or embryo.
Developmental stage	Developmental stage: Developmental stage of the oocyte or embryo. Coded Text Oocyte Pronuclear stage 2-cell stage 4-cell stage 8-cell stage Morula Blastocyst Text
Developmental event	Developmental event: Recording of a developmental event observed during time-lapse microscopy. May record timed events, like extrusion of second polar body, appearance and fading of pronuclei, cell divisions, or compaction. Text Coded Text tPB2 extrusion tPNa tPNf t2 t3 t4 t5 t6 t7 t8 tSC tM tSB tB tE tHN tHB
Examination of a cleavage-stage embryo	Examination of a cleavage-stage embryo: Morphological findings obtained by microscopy of the human cleavage-stage embryo during assisted reproduction treatment.
Number of cells	Number of cells: Number of cells in a cleavage-stage embryo.
Fragmentation	Fragmentation: Cytoplasmic fragmentation in a cleavage stage embryo. Coded Text None Mild fragmentation Moderate fragmentation Severe fragmentation Text Proportion
Blastomere size	Blastomere size: Relative blastomere size. Coded Text Equal Unequal Stage specific Non-stage specific Text
Nucleation	Nucleation: Presence or absence of nuclei in the blastomeres of the cleavage stage embryo. Coded Text No visible nuclei Mononucleation Binucleation Multinucleation Broad multinucleation Text
Cytoplasmic morphology	Cytoplasmic morphology: Morphology of the cytoplasm of cells in cleavage stage embryo. May contain description of abnomalies, such as granularity, pitting, and presence of vacuoles.
Spatial distribution of cells	Spatial distribution of cells: Spatial distribution of cells in a cleavage stage embryo. The cells of early embryo may be arranged in pyramidal, clover or irregular manner.
Compaction	Compaction: Degree of compaction in a cleavage stage embryo. Coded Text None Minimal Moderate Complete Text
Other morphological features	Other morphological features: Additional morphological features not captured by specific parameters.
Examination of a blastocyst	Examination of a blastocyst: Morphological findings obtained by microscopy of the human blastocyst during assisted reproduction treatment.
Degree of expansion	Degree of expansion: Degree of expansion of the blastocyst. Coded Text Grade 1 Grade 2 Grade 3 Grade 4 Grade 5 Grade 6 Text
Inner cell mass morphology	Inner cell mass morphology: Morphology of the inner cell mass. Coded Text A B C Not accessible Text
Trophectoderm morphology	Trophectoderm morphology: Morphology of the trophectoderm of the blastocyst. Coded Text A B C Text
Other morphological features	Other morphological features: Additional morphological features of the blastocyst not captured by specific parameters. May include signs of degeneration, such as presence of necrosis and exclusion of cells, cellular bridges, vacuolation, multiple hatching points.
Time post-insemination	Time post-insemination: The duration since insemination.
Interpretation	Interpretation: Clinical interpretation of the morphological and developmental assessment of the oocyte or embryo. Coded Text Suitable for clinical use Unsuitable for clinical use Text
Comment	Comment: Additional narrative about the oocyte or embryo assessment, not captured in other fields. For example: difficulties in visualisation.
Day-4 embryo assessment	Day-4 embryo assessment: Embryo observation on Day 4 post insemination.
Data
Label	Label: Label or name identifying an oocyte or embryo.
ID	ID: The unique identifier for the oocyte or embryo. For example: the "Single European Code” or “SEC” identifier.
Description	Description: General description of the oocyte or embryo.
Developmental stage	Developmental stage: Developmental stage of the oocyte or embryo. Coded Text Oocyte Pronuclear stage 2-cell stage 4-cell stage 8-cell stage Morula Blastocyst Text
Developmental event	Developmental event: Recording of a developmental event observed during time-lapse microscopy. May record timed events, like extrusion of second polar body, appearance and fading of pronuclei, cell divisions, or compaction. Text Coded Text tPB2 extrusion tPNa tPNf t2 t3 t4 t5 t6 t7 t8 tSC tM tSB tB tE tHN tHB
Examination of a blastocyst	Examination of a blastocyst: Morphological findings obtained by microscopy of the human blastocyst during assisted reproduction treatment.
Degree of expansion	Degree of expansion: Degree of expansion of the blastocyst. Coded Text Grade 1 Grade 2 Grade 3 Grade 4 Grade 5 Grade 6 Text
Inner cell mass morphology	Inner cell mass morphology: Morphology of the inner cell mass. Coded Text A B C Not accessible Text
Trophectoderm morphology	Trophectoderm morphology: Morphology of the trophectoderm of the blastocyst. Coded Text A B C Text
Other morphological features	Other morphological features: Additional morphological features of the blastocyst not captured by specific parameters. May include signs of degeneration, such as presence of necrosis and exclusion of cells, cellular bridges, vacuolation, multiple hatching points.
Time post-insemination	Time post-insemination: The duration since insemination.
Interpretation	Interpretation: Clinical interpretation of the morphological and developmental assessment of the oocyte or embryo. Coded Text Suitable for clinical use Unsuitable for clinical use Text
Comment	Comment: Additional narrative about the oocyte or embryo assessment, not captured in other fields. For example: difficulties in visualisation.
Day-5 embryo assessment	Day-5 embryo assessment: Embryo observation on Day 5 post insemination.
Data
Label	Label: Label or name identifying an oocyte or embryo.
ID	ID: The unique identifier for the oocyte or embryo. For example: the "Single European Code” or “SEC” identifier.
Description	Description: General description of the oocyte or embryo.
Developmental stage	Developmental stage: Developmental stage of the oocyte or embryo. Coded Text Oocyte Pronuclear stage 2-cell stage 4-cell stage 8-cell stage Morula Blastocyst Text
Developmental event	Developmental event: Recording of a developmental event observed during time-lapse microscopy. May record timed events, like extrusion of second polar body, appearance and fading of pronuclei, cell divisions, or compaction. Text Coded Text tPB2 extrusion tPNa tPNf t2 t3 t4 t5 t6 t7 t8 tSC tM tSB tB tE tHN tHB
Examination of a blastocyst	Examination of a blastocyst: Morphological findings obtained by microscopy of the human blastocyst during assisted reproduction treatment.
Degree of expansion	Degree of expansion: Degree of expansion of the blastocyst. Coded Text Grade 1 Grade 2 Grade 3 Grade 4 Grade 5 Grade 6 Text
Inner cell mass morphology	Inner cell mass morphology: Morphology of the inner cell mass. Coded Text A B C Not accessible Text
Trophectoderm morphology	Trophectoderm morphology: Morphology of the trophectoderm of the blastocyst. Coded Text A B C Text
Other morphological features	Other morphological features: Additional morphological features of the blastocyst not captured by specific parameters. May include signs of degeneration, such as presence of necrosis and exclusion of cells, cellular bridges, vacuolation, multiple hatching points.
Time post-insemination	Time post-insemination: The duration since insemination.
Interpretation	Interpretation: Clinical interpretation of the morphological and developmental assessment of the oocyte or embryo. Coded Text Suitable for clinical use Unsuitable for clinical use Text
Comment	Comment: Additional narrative about the oocyte or embryo assessment, not captured in other fields. For example: difficulties in visualisation.
Freezing assessment	Freezing assessment: Oocyte or embryo observation at cryopreservation.
Data
Label	Label: Label or name identifying an oocyte or embryo.
ID	ID: The unique identifier for the oocyte or embryo. For example: the "Single European Code” or “SEC” identifier.
Description	Description: General description of the oocyte or embryo.
Developmental stage	Developmental stage: Developmental stage of the oocyte or embryo. Coded Text Oocyte Pronuclear stage 2-cell stage 4-cell stage 8-cell stage Morula Blastocyst Text
Developmental event	Developmental event: Recording of a developmental event observed during time-lapse microscopy. May record timed events, like extrusion of second polar body, appearance and fading of pronuclei, cell divisions, or compaction. Text Coded Text tPB2 extrusion tPNa tPNf t2 t3 t4 t5 t6 t7 t8 tSC tM tSB tB tE tHN tHB
Examination of a blastocyst	Examination of a blastocyst: Morphological findings obtained by microscopy of the human blastocyst during assisted reproduction treatment.
Degree of expansion	Degree of expansion: Degree of expansion of the blastocyst. Coded Text Grade 1 Grade 2 Grade 3 Grade 4 Grade 5 Grade 6 Text
Inner cell mass morphology	Inner cell mass morphology: Morphology of the inner cell mass. Coded Text A B C Not accessible Text
Trophectoderm morphology	Trophectoderm morphology: Morphology of the trophectoderm of the blastocyst. Coded Text A B C Text
Other morphological features	Other morphological features: Additional morphological features of the blastocyst not captured by specific parameters. May include signs of degeneration, such as presence of necrosis and exclusion of cells, cellular bridges, vacuolation, multiple hatching points.
Time post-insemination	Time post-insemination: The duration since insemination.
Interpretation	Interpretation: Clinical interpretation of the morphological and developmental assessment of the oocyte or embryo. Coded Text Suitable for clinical use Unsuitable for clinical use Text
Comment	Comment: Additional narrative about the oocyte or embryo assessment, not captured in other fields. For example: difficulties in visualisation.
Thawing assessment	Thawing assessment: Oocyte or embryo observation at thawing.
Data
Label	Label: Label or name identifying an oocyte or embryo.
ID	ID: The unique identifier for the oocyte or embryo. For example: the "Single European Code” or “SEC” identifier.
Description	Description: General description of the oocyte or embryo.
Developmental stage	Developmental stage: Developmental stage of the oocyte or embryo. Coded Text Oocyte Pronuclear stage 2-cell stage 4-cell stage 8-cell stage Morula Blastocyst Text
Developmental event	Developmental event: Recording of a developmental event observed during time-lapse microscopy. May record timed events, like extrusion of second polar body, appearance and fading of pronuclei, cell divisions, or compaction. Text Coded Text tPB2 extrusion tPNa tPNf t2 t3 t4 t5 t6 t7 t8 tSC tM tSB tB tE tHN tHB
Examination of a blastocyst	Examination of a blastocyst: Morphological findings obtained by microscopy of the human blastocyst during assisted reproduction treatment.
Degree of expansion	Degree of expansion: Degree of expansion of the blastocyst. Coded Text Grade 1 Grade 2 Grade 3 Grade 4 Grade 5 Grade 6 Text
Inner cell mass morphology	Inner cell mass morphology: Morphology of the inner cell mass. Coded Text A B C Not accessible Text
Trophectoderm morphology	Trophectoderm morphology: Morphology of the trophectoderm of the blastocyst. Coded Text A B C Text
Other morphological features	Other morphological features: Additional morphological features of the blastocyst not captured by specific parameters. May include signs of degeneration, such as presence of necrosis and exclusion of cells, cellular bridges, vacuolation, multiple hatching points.
Time post-insemination	Time post-insemination: The duration since insemination.
Interpretation	Interpretation: Clinical interpretation of the morphological and developmental assessment of the oocyte or embryo. Coded Text Suitable for clinical use Unsuitable for clinical use Text
Comment	Comment: Additional narrative about the oocyte or embryo assessment, not captured in other fields. For example: difficulties in visualisation.
Embryo transfer assessment	Embryo transfer assessment: Embryo observation at embryo transfer.
Data
Label	Label: Label or name identifying an oocyte or embryo.
ID	ID: The unique identifier for the oocyte or embryo. For example: the "Single European Code” or “SEC” identifier.
Description	Description: General description of the oocyte or embryo.
Developmental stage	Developmental stage: Developmental stage of the oocyte or embryo. Coded Text Oocyte Pronuclear stage 2-cell stage 4-cell stage 8-cell stage Morula Blastocyst Text
Developmental event	Developmental event: Recording of a developmental event observed during time-lapse microscopy. May record timed events, like extrusion of second polar body, appearance and fading of pronuclei, cell divisions, or compaction. Text Coded Text tPB2 extrusion tPNa tPNf t2 t3 t4 t5 t6 t7 t8 tSC tM tSB tB tE tHN tHB
Examination of a blastocyst	Examination of a blastocyst: Morphological findings obtained by microscopy of the human blastocyst during assisted reproduction treatment.
Degree of expansion	Degree of expansion: Degree of expansion of the blastocyst. Coded Text Grade 1 Grade 2 Grade 3 Grade 4 Grade 5 Grade 6 Text
Inner cell mass morphology	Inner cell mass morphology: Morphology of the inner cell mass. Coded Text A B C Not accessible Text
Trophectoderm morphology	Trophectoderm morphology: Morphology of the trophectoderm of the blastocyst. Coded Text A B C Text
Other morphological features	Other morphological features: Additional morphological features of the blastocyst not captured by specific parameters. May include signs of degeneration, such as presence of necrosis and exclusion of cells, cellular bridges, vacuolation, multiple hatching points.
Time post-insemination	Time post-insemination: The duration since insemination.
Interpretation	Interpretation: Clinical interpretation of the morphological and developmental assessment of the oocyte or embryo. Coded Text Suitable for clinical use Unsuitable for clinical use Text
Comment	Comment: Additional narrative about the oocyte or embryo assessment, not captured in other fields. For example: difficulties in visualisation.
Protocol
Culture dish ID	Culture dish ID: The unique identifier for the culture dish containing the oocyte or embryo.
Method	Method: Method for assessment of morphology and development of the oocyte or embryo. Coded Text Manual Time-lapse Text