ARCHETYPE Examination of a zygote (openEHR-EHR-CLUSTER.exam_zygote.v0)

ARCHETYPE IDopenEHR-EHR-CLUSTER.exam_zygote.v0
ConceptExamination of a zygote
DescriptionMorphological findings obtained by microscopy of the human zygote during assisted reproduction treatment.
UseUse to record morphological observations appropriate for the zygote stage during assisted reproduction treatment. This archetype has been specifically designed to be used in the 'Observations detail' SLOT within the 'OBSERVATION.embryo' or 'ACTION.procedure' archetype, but can also be used within other ENTRY or CLUSTER archetypes, where clinically appropriate.
MisuseNot to be used for recording observations on oocytes, cleavage stage embryos and blastocysts - use specific CLUSTER archetypes for this purpose.
PurposeTo record structured observations of the human zygote during assisted reproduction treatment.
ReferencesAlpha Scientists in Reproductive, M. and E.S.I.G.o. Embryology, The Istanbul consensus workshop on embryo assessment: proceedings of an expert meeting. Human Reproduction, 2011. 26(6): p. 1270-1283.

Papale, L., et al., The zygote. Human Reproduction, 2012. 27(suppl_1): p. i22-i49.
Copyright© openEHR Foundation
AuthorsAuthor name: Peter Fedorcsak
Organisation: Oslo University Hospital
Email: peter.fedorcsak@medisin.uio.no
Date originally authored: 2021-10-26
Other Details LanguageAuthor name: Peter Fedorcsak
Organisation: Oslo University Hospital
Email: peter.fedorcsak@medisin.uio.no
Date originally authored: 2021-10-26
OtherDetails Language Independent{licence=This work is licensed under the Creative Commons Attribution-ShareAlike 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-sa/4.0/., custodian_organisation=openEHR Foundation, references=Alpha Scientists in Reproductive, M. and E.S.I.G.o. Embryology, The Istanbul consensus workshop on embryo assessment: proceedings of an expert meeting. Human Reproduction, 2011. 26(6): p. 1270-1283. Papale, L., et al., The zygote. Human Reproduction, 2012. 27(suppl_1): p. i22-i49., original_namespace=org.openehr, original_publisher=openEHR Foundation, custodian_namespace=org.openehr, MD5-CAM-1.0.1=9C03BF57FB64484447801268561C850F, build_uid=3a84f707-f6ba-4d63-932c-e538a9499d9f, ip_acknowledgements=This artefact includes content from SNOMED Clinical Terms® (SNOMED CT®) which is copyrighted material of the International Health Terminology Standards Development Organisation (IHTSDO). Where an implementation of this artefact makes use of SNOMED CT content, the implementer must have the appropriate SNOMED CT Affiliate license - for more information contact https://www.snomed.org/snomed-ct/get-snomed or info@snomed.org., revision=0.0.1-alpha}
Keywordsin vitro, fertilization, IVF, reproductive medicine, zygote, fertilised, fertilized, oocyte, egg, fertilisation, embryo, reproduction, ART, blastocyst
Lifecyclein_development
UID855eb6e8-e203-4652-8d02-e5c3aa795c41
Language useden
Citeable Identifier1013.1.5830
Revision Number0.0.1-alpha
AllArchetype [runtimeNameConstraintForConceptName=null, archetypeConceptBinding=null, archetypeConceptDescription=Morphological findings obtained by microscopy of the human zygote during assisted reproduction treatment., archetypeConceptComment=null, otherContributors=Vebjørn Arntzen, Oslo University Hospital, Norway (openEHR Editor)
Peter Fedorcsak, University of Oslo, Norway (openEHR Editor)
Liv Laugen, ​Oslo University Hospital, Norway, Norway (openEHR Editor)
Heather Leslie, Atomica Informatics, Australia (openEHR Editor)
Trine Skuland, Oslo University Hospital
Gareth Greggains, Oslo University Hospital, originalLanguage=en, translators=Norwegian Bokmål: Peter Fedorcsak, University of Oslo, peterfe@uio.no
, subjectOfData=unconstrained, archetypeTranslationTree=null, topLevelToAshis={ism_transition=[], relationships=[], target=[], items=[ResourceSimplifiedHierarchyItem [path=/items[at0005], code=at0005, itemType=ELEMENT, level=1, text=Number of pronuclei, description=Number of visible pronuclei in a zygote., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_COUNT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001], code=at0001, itemType=ELEMENT, level=1, text=Pronuclear symmetry, description=Size symmetry of pronuclei in a zygote., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CHOICE, bindings=null, values=Choice of:
  •  Text
  •  Coded Text
    • Symmetrical [Evenly sized pronuclei.]
    • Non-symmetrical [Difference between pronuclear size.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0002], code=at0002, itemType=ELEMENT, level=1, text=Pronuclear morphology, description=Morphology of pronuclei in a zygote., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CHOICE, bindings=null, values=Choice of:
  •  Text
  •  Coded Text
    • Centrally juxtaposed [Centrally located, juxtaposed pronuclei.]
    • Separated [Separated pronuclei.]
    • Peripherally positioned [Peripherally located pronuclei.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0003], code=at0003, itemType=ELEMENT, level=1, text=Polar body morphology, description=Morphology of polar bodies in a zygote., comment=null, uncommonOntologyItems=null, occurencesFormal=0..*, occurencesText=Optional, repeating, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CHOICE, bindings=null, values=Choice of:
  •  Text
  •  Coded Text
    • Normal [Juxtaposed polar bodies.]
    • Separated [Large angle between polar bodies.]
    • Fragmented [Fragmented polar bodies.]
    • Degenerated [Degenerated or atretic polar bodies.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0004], code=at0004, itemType=ELEMENT, level=1, text=Cytoplasmic morphology, description=Morphology of the cytoplasm in a zygote., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CHOICE, bindings=null, values=Choice of:
  •  Text
  •  Coded Text
    • Homogeneous [Homogeneous cytoplasm.]
    • Granular [Granular cytoplasm.]
    • Vacuolated [Vacuolated cytoplasm, including small and large vacuoles.]
    • Dysmorphic [Dysmorphic cytoplasm, including clustered organelles.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0019], code=at0019, itemType=ELEMENT, level=1, text=Nucleolar precursor bodies, description=Distribution of nuclear precursor bodies in a zygote., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CHOICE, bindings=null, values=Choice of:
  •  Coded Text
    • Normal [Several nuclear precursor bodies.]
    • Absent [Absent nuclear precursor body.]
    • Bull's eye [Pronuclei with 1 nuclear precursor body.]
  •  Text
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0028], code=at0028, itemType=ELEMENT, level=1, text=Other morphological features, description=Additional morphological features not captured by specific parameters., comment=null, uncommonOntologyItems=null, occurencesFormal=0..*, occurencesText=Optional, repeating, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null]], protocol=[], identities=[], state=[], events=[], content=[], source=[], capabilities=[], other_participations=[], details=[], context=[], activities=[], contacts=[], data=[], credentials=[], provider=[], description=[]}, topLevelItems={items=ResourceSimplifiedHierarchyItem [path=ROOT_/, code=at0000, itemType=CLUSTER, level=0, text=null, description=null, comment=null, uncommonOntologyItems=null, occurencesFormal=1..1, occurencesText=Mandatory, cardinalityFormal=1..*, cardinalityText=, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=null, extendedValues=null]}, addHierarchyItemsTo=items, currentHierarchyItemsForAdding=[ResourceSimplifiedHierarchyItem [path=/items[at0005], code=at0005, itemType=ELEMENT, level=1, text=Number of pronuclei, description=Number of visible pronuclei in a zygote., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_COUNT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001], code=at0001, itemType=ELEMENT, level=1, text=Pronuclear symmetry, description=Size symmetry of pronuclei in a zygote., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CHOICE, bindings=null, values=Choice of:
  •  Text
  •  Coded Text
    • Symmetrical [Evenly sized pronuclei.]
    • Non-symmetrical [Difference between pronuclear size.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0002], code=at0002, itemType=ELEMENT, level=1, text=Pronuclear morphology, description=Morphology of pronuclei in a zygote., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CHOICE, bindings=null, values=Choice of:
  •  Text
  •  Coded Text
    • Centrally juxtaposed [Centrally located, juxtaposed pronuclei.]
    • Separated [Separated pronuclei.]
    • Peripherally positioned [Peripherally located pronuclei.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0003], code=at0003, itemType=ELEMENT, level=1, text=Polar body morphology, description=Morphology of polar bodies in a zygote., comment=null, uncommonOntologyItems=null, occurencesFormal=0..*, occurencesText=Optional, repeating, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CHOICE, bindings=null, values=Choice of:
  •  Text
  •  Coded Text
    • Normal [Juxtaposed polar bodies.]
    • Separated [Large angle between polar bodies.]
    • Fragmented [Fragmented polar bodies.]
    • Degenerated [Degenerated or atretic polar bodies.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0004], code=at0004, itemType=ELEMENT, level=1, text=Cytoplasmic morphology, description=Morphology of the cytoplasm in a zygote., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CHOICE, bindings=null, values=Choice of:
  •  Text
  •  Coded Text
    • Homogeneous [Homogeneous cytoplasm.]
    • Granular [Granular cytoplasm.]
    • Vacuolated [Vacuolated cytoplasm, including small and large vacuoles.]
    • Dysmorphic [Dysmorphic cytoplasm, including clustered organelles.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0019], code=at0019, itemType=ELEMENT, level=1, text=Nucleolar precursor bodies, description=Distribution of nuclear precursor bodies in a zygote., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CHOICE, bindings=null, values=Choice of:
  •  Coded Text
    • Normal [Several nuclear precursor bodies.]
    • Absent [Absent nuclear precursor body.]
    • Bull's eye [Pronuclei with 1 nuclear precursor body.]
  •  Text
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0028], code=at0028, itemType=ELEMENT, level=1, text=Other morphological features, description=Additional morphological features not captured by specific parameters., comment=null, uncommonOntologyItems=null, occurencesFormal=0..*, occurencesText=Optional, repeating, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null]], minIndents={}, termBindingRetrievalErrorMessage=null]